Gynecomastia is a condition that causes excess breast tissue to develop in men, resulting in a more feminine chest. It can be caused by an imbalance of hormones, genetics, or certain medications. Gynecomastia can affect men and boys of all ages, but it's most common in teenage boys.
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Common causes of gynecomastia include hormonal shifts that create a high estrogen to androgen ratio, as well as conditions that lead to low testosterone production such as hypogonadism. The condition can be a side effect of certain medications such as anti-androgens used to treat prostate cancer, ulcer medications such as cimetidine, we well as antibiotics, tricyclic antidepressants, anti-anxiety medications like diazepam, certain inhibitors, spironolactone, and even illegal drugs including anabolic steroids, marijuana, and amphetamines. Gynecomastia can also be caused by genetic predisposition, and medical conditions including thyroid disorders such as hyperthyroidism, or less commonly by testicular cancer, tumors involving the testes, adrenal or pituitary gland, as well as changes in hormone levels related to cirrhosis, liver disease, kidney disease, and kidney failure, but in most cases the cause of gynecomastia is idiopathic (unknown).
Gynecomastia is diagnosed with a review of your family history, a physical examination, a blood test to check hormone levels, and possibly a mammogram or ultrasound to see detailed images of breast tissue.
The prevalence of gynecomastia is approximately 50-60% in adolescent boys, and 65% in men aged 27 to 92 years of age.